CROW meeting time

Hi everyone-
Thanks for the great REDcap demo yesterday - it looks like a very useful database tool! I'm looking forward to Connie's disucssion next week. I am wondering if during that meeting we can also think about changing our meeting time for the fall semester? I am teaching a course that is scheduled during our regular time slot.
thanks!
Abby

Clinical Research Oriented Workshop plan for this Wednesday - REDCap Demo

Hi All,

Just wanted to provide some background for tomorrow's REDCap demo that will be provided by Diantha Howard.

REDCap (Research Electronic Data Capture) is a software toolset and workflow methodology developed at Vanderbilt University for electronic collection and management of research and clinical trial data. UVM has joined the REDCap Consortium and offers both applications (REDCap and REDCap Survey) to UVM/FAHC researchers. More information can be found at the following Web sites:

http://www.project-redcap.org/
http://www.uvm.edu/~ccts/web/informatics/redcap

The attached article also provides additional details:
Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG.
Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.
J Biomed Inform. 2009 Apr;42(2):377-81.

The CCTS Informatics Unit is aiming to start providing REDCap Training Sessions to investigators in the coming months and would like to pilot this session with the CROW group. Any feedback regarding the content and format afterwards will be appreciated.

Hope to see you there!

Thanks.

-Liz

Fwd: Informatics Grand Rounds - Fall 2010 Schedule and Mailing List

---------- Forwarded message ----------
From: "Liz Chen" <liz.chen@uvm.edu>
Date: Aug 2, 2010 3:41 PM
Subject: Informatics Grand Rounds - Fall 2010 Schedule and Mailing List
To: <INFORMATICS-GR@list.uvm.edu>

Welcome to the Informatics Grand Rounds mailing list! This list will mainly be used to post announcements about upcoming events.

FALL 2010 SCHEDULE

Monthly presentations will resume in the Fall on Tuesdays 4-5 PM in the UVM/FAHC Medical Education Center Room 300 with the following schedule of speakers:

September 14
David Cochran, MD (Vermont Information Technology Leaders [VITL])

October 5
Craig Jones, MD (Vermont Blueprint for Health)

November 2
Marianne Burke, MLS, AHIP (Dana Medical Library, University of Vermont)

December 14
Richard B. Colletti, MD (Department of Pediatrics, University of Vermont College of Medicine and Vermont Children's Hospital, Fletcher Allen Health Care)
Keith Marsolo, PhD (Children's Hospital Research Foundation, Cincinnati Children's Hospital Medical Center and University of Cincinnati)

This schedule can be found on the following Web site, which also includes links to presentations from the inaugural session on June 29:
http://www.uvm.edu/~ccts/web/informatics/grandrounds

MAILING LIST INSTRUCTIONS

If you wish to be removed from this list, you may send an email to listserv@list.uvm.edu with the following command in the body of the message:

unsub informatics-gr

If there are others who may be interested in subscribing, please feel free to forward this message and they may send an email to listserv@list.uvm.edu with the following command in the body of the message:

sub informatics-gr your_name_here

where "your_name_here" should be replaced with your first and last name (e.g., sub informatics-gr Mary Smith)

Alternatively, please feel free to contact me anytime to be removed/added from the list or with any questions/comments about the Informatics Grand Rounds.

Best,

-Liz

--
~~~~~~~~~~~~~~~~~~
Elizabeth S. Chen, PhD
Associate Director of Biomedical Informatics
   Center for Clinical and Translational Science
Assistant Professor
   Department of Medicine - General Internal Medicine
   Department of Computer Science

University of Vermont
89 Beaumont Avenue, Given Courtyard N311
Burlington, VT 05405

Tel: 802.656.8286
Fax: 802.656.4589
Email: liz.chen@uvm.edu
Web: www.uvm.edu/~eschen

Clinical Research Oriented Workshop (CROW) Meeting: July 28, 2010

Present: Amanda Kennedy, Rodger Kessler, Ben Littenberg, Charlie MacLean, Carole McBride, Connie van Eeghen (via Skype)

1. Round Table: Rodger wanted to know if, after starting a grant, if the staff aren’t hired until later, what happens to the funds? Ben: most grants have flexible funding, such that unspent funds can be rebudgeted to another line item in the project (assuming appropriate expenses, of course). There is usually a 25% limit before reporting is necessary. Money can also be rolled over to the next year and can be asked to extend the project for longer than the grant originally was limited to.

2. Carole’s Discussion: To what degree are the poor outcomes related to pregnancy/childbirth after IVF conception related to the intervention vs. the underlying medical issues?

a. Considered different ways of constructing a study. Issues included:
i. Separately studying the anovulatory subjects as a group
ii. Focusing on one specific intervention
iii. Variations in qualification for IVF
iv. Comparisons between the outcomes of different diagnoses related to pregnancy which were treated by the same intervention
v. High volume of data needed
vi. Comparisons between mothers of the same age (and other characteristics) with different histories of an intervention, although the ability to explain may not be high
b. Next step is to narrow done what can be studied to move in one of the above directions
i. Do the traditional risks apply in the population?
ii. What are the key risk factors for this population?
iii. Differences in geographic/national/cultural populations?
iv. Study the complication rate by treatment.
v. Study the time taken to delivery in good and bad outcome cases, adjusting for interventions: P(obstetric misadventure|conception) = f(time since diagnosis & age & maternal weight & treatment intensity)
1. Depends on a model of toxicity of treatment, e.g. does it wear off over time or is it permanent
2. Analysis by different negative outcomes, e.g. low birth weight
c. Approach: data base request to DBA – ask for unfiltered data; do the filters yourself
3. Amanda’s question: student approach to research
a. Writing a protocol for a physician for which the plan is for paramedics to intubate in the field
b. ED docs to conduct a field based RCT for two different airway procedures
i. Primary outcome: success with ventilation (not yet specified)
ii. Randomize by day of month, e.g. Wednesday codes are procedure A.
iii. Question: can the codes be randomized by day or should they be randomized by event
1. Can be randomized by day but introduces clustering without need; needs to be controlled
2. Risk of non-compliance for paramedics is worth considering
3. Consider randomizing the paramedic, rather than the day
4. Best scenario: identifying the intervention after the decision has been made to intubate
c. Key: the study team needs to know that the flaws in the design gives ammunition to those who decide, once the results are complete, that they are not happy

4. Next Fellows Meeting(s): Wednesday, 2:00 – 3:30 p.m., at Given Courtyard Level 4
a. Aug 4: Diantha Howard and Liz Chen: REDCap training (no Connie, Matt) – NOTE NEW LOCATION: 3rd floor (S359)
b. Aug 11: Connie’s qualitative study on quality – members will be asked to perform analysis; slides to be mailed out one week ahead (no Matt). Need to start at 2:30
c. Aug 18: (No Connie)
d. Aug 25:
e. Future agenda to consider:
i. Rodger: Mixed methods article
ii. Future: Review of different types of journal articles (lit review, case study, original article, letter to editor…), when each is appropriate, tips on planning/writing (Abby)
iii. Future: Informed consent QI: Connie to follow up with Nancy Stalnaker, Alan Rubin will follow up with Alan Wortheimer or Rob McCauly
iv. Kairn will ask a librarian to join us for selected issues

5. Fellows document – nothing this time – to be reviewed after trialing Wednesday meeting times, which started May 5, 2010.

Recorder: Connie van Eeghen

Funding: Training Grants at AHRQ

AHRQ has updated its website about training grants for students and post-docs. Of special interest:

Pre-doctoral

• Health Services Research Dissertation Awards (R36)
  Dissertation grants for doctoral candidates.
  Note: New Receipt Dates for Dissertation Applications-February, May, August, and November 1 annually (beginning November 1, 2009).

Post-doctoral

• Individual Postdoctoral Fellowship Awards (F32)
  Available to applicants who have completed their clinical or research doctoral degrees.
• Career Development Awards — FOAs for these programs have been updated to reflect the new requirements from NIH's Enhancing Peer Review Initiative. The new requirements are effective for submissions intended for due dates January 25, 2010 and beyond. If submitting an application intended for a due date of January 25, 2010 and beyond, follow the guidance and be sure to use the Adobe-Forms-B version of the application forms and instructions.
  • Mentored Research Scientist Development Award (K01)
    Health services research career preparation support for emerging scientists with research doctorates.
  • Independent Scientist Awards (K02)
    Career development support for newly-minted clinical and research investigators.
  • Mentored Clinical Scientist Development Awards (K08)
    Health services research career preparation support for emerging clinical scientists.

Vermont Vascular Medicine Conference - August Edition

Hello all,

Welcome to an early start to the Fall semester of the Vermont Vascular Medicine Conference!

The next VVM Conference will be on August 20, 9:15-10:15. I will be speaking on, "D-dimer in Disease: Clinical and Research Applications." I'll talk about typical clinical use of the test, discuss relationships of D-dimer with diseases ranging from thrombosis to aging and frailty, and what we are learning about these diseases through study of D-dimer.

 Here is the completed fall schedule of speakers and topics. We have a great mix of interdisciplinary topics and I am greatly looking forward to all of these talks!

September 17:  Richard Pratley, MD, Endocrinology.  BARI2D trial and update on thiazolidinediones (TZDs)

October 15:  Russell Tracy, PhD, Pathology and Biochemistry. Hypercoagulable State of HIV

November 19: Friederike Keating, MD, Cardiology. Use of Transfusions in Coronary Disease Patients

December 17: Gilman Allen, MD, Pulmonary. Hemostasis and Lung Pathology/Disease

This conference is devoted to disseminating information on diverse topics broadly related to vascular medicine, that include clinical and research topics of interest to those at UVM and FAHC. The purpose is to promote collaboration and interchange on clinical and research topics across disciplines at all levels; from students to professors, and including information of use to anyone involved in the care of patients with vascular diseases. Presentations are fairly casual, allowing ample discussion, and are accompanied by a light breakfast.

Vermont Vascular Medicine Conference

An Interdisciplinary Conference devoted to

Hemostasis, Thrombosis, and Vascular Medicine

 

Date:  Friday, August 20, 2009

Time:  9:15 – 10:15 am

Place:  HSRF 400 

 

Speaker: 

Mary Cushman, MD, MSc

Professor of Medicine

Director, Thrombosis and Hemostasis Program

 

Title: 

D-dimer in Disease: Clinical and Research Applications

 

Light breakfast will be served

Mary Cushman, MD, MSc

Professor of Medicine

University of Vermont and Fletcher Allen Health Care

208 South Park Drive

Colchester, VT 05446

phone:   802-656-8968

fax:  802-656-8965

 

Fwd: FW: MD-PhD Annual Research Day

--Ben Littenberg

---------- Forwarded message ----------
From: "Gillett, Sarah R" <Sarah.Gillett@uvm.edu>
Date: Jul 22, 2010 1:00 PM
Subject: FW: MD-PhD Annual Research Day
To: "Benjamin Littenberg (littenbl@gmail.com)" <littenbl@gmail.com>

I assume you guys got this from the source, but just in case you didn’t….

 

 Come to research day!  Your two CTS MD/PhD people are presenting right after lunch (me at 12:40 and Gabe at 1) and I would love to see you there…

 

Ben, perhaps you can post to the blog?
Sarah

 

From: Taylor, Maranda
Sent: Monday, July 19, 2010 1:30 PM
To: Gillett, Sarah R
Subject: RE: MD-PhD Annual Research Day

 

Hi Sarah,

 

I’ve attached a PDF of the program.  I hope this is helpful!

 

Maranda

 

From: Gillett, Sarah R
Sent: Monday, July 19, 2010 1:19 PM
To: Taylor, Maranda
Subject: RE: MD-PhD Annual Research Day

 

Hi!

Do you have the actual schedule of when each student will present? I have some people who may want to come.

 

From: Taylor, Maranda
Sent: Monday, July 19, 2010 8:11 AM
To: All MD-PhD Students; 'Gale.Golden@uvm.edu'; Nachbur, Jennifer; Budd, Ralph; Cipolla, Marilyn J; Forehand, Cynthia J; Fukagawa, Naomi - Preferred e-mail; Grant, Barbara W.; 'Grasso, Domenico'; Higgins, Stephen; Irvin, Charles G; Jaworski, Diane; Johnson, Robert J.; Kirkpatrick, Beth D.; LeWinter, Martin M.; Mann, Kenneth G.; McLaughlin, Emily A; Montgomery, Erin; Mossman, Brooke T; Naylor M.D., Magdalena; Pederson, David; 'Stokowski, Patricia'; Teuscher, Cory; Tracy, Russell P; Young, Roger C; Bosenberg, Marcus W; Huston, Christopher D.; Janssen-Heininger, Yvonne M; Krag, David N; Lounsbury, Karen M.; Mao-Draayer, Yang; Morrical, Scott; Nishi, Rae; Poynter, Matthew E; Pratley, Richard E; Rincon, Mercedes; Spees, Jeffrey L; Tracy, Paula B; Wallace, Susan; Ward, Gary; Beaulieu, Lisa; Chauncey, Ann; Faustner, Emma K; Frey, Audree; Hurwitz, Aaron; Keirnan, Mary Lou; Leahy, James P; McCrea, Laurie; Perkins, Carrie I; Pratt, Elizabeth F; Youngberg, Sheri L; Delaney, Tiffany J; Forguites, Patricia A; Jewkes, Cary R; Keefe, Mary E; Sladyk, Shona; Aspinall, Jane A; Blount, Rick J; Fuller, Benjamin H; Gilbert, James; Gildea, Cristin; Healy, Michael Jay; Keblin, Sarah; Lubkowitz, Ginger; Morrison, Travis H; O'Connor, Manon; 'Barry Finette'; Bonney, Elizabeth A; 'Brayden, Joseph'; Curley, David P; Dimick, Ellen M.; Doublié, Sylvie; Galbraith, Richard A.; Hudziak, James J; 'Lidofsky, Steven'; Mawe, Gary; Meyer, Marjorie C.; Ogle, Jeri L; Weiss, Daniel J; Bovill, Edwin G; Braff, Steven P.; First, Lewis R; Hamill, Robert W; McFadden, David; Nelson, Mark T.; Nichols, Claude E; Parsons, Polly E.; 'Parsons, Rodney'; Peterson, Thomas C; 'Phillippe, Mark'; Pierattini, Robert A.; Schapiro, Howard M.; Wallace, Susan; Warshaw, David
Cc: Randall, Maura L; Waterman, G. Scott; Jeffries, William; Gallant, Janice M; Bernstein, Ira M
Subject: RE: MD-PhD Annual Research Day

 

YOU’RE INVITED TO

THE UVM COLLEGE OF MEDICINE

 

Seventh Annual

MD PhD RESEARCH DAY

 

Friday, July 23, 2010

Med Ed 200

8:00am—3:30pm

 

Welcome � Steven D. Lidofsky, M.D., Ph.D., Program Director  8:45a.m.

 

MD � PhD students present their research 9:00am—2:00pm

 

Keynote Address by Gyongyi Szabo, M.D., Ph.D.,

 

Professor, Associate Dean for Clinical and Translational Science, Director of Hepatology and

Liver Center, University of Massachusetts Medical School. 2:20pm

 

Closing Reception

 

 

 

 

 

 

 

 

 

 

 

MD PhD Office

The Courtyard at Given, N-106

89 Beaumont Ave.

Burlington, VT 05405