Friday, September 12, 2014

Clinical Research Oriented Workshop (CROW) Meeting: Sept 11, 2014



Present:  Kairn Kelley, Amanda Kennedy, Ben Littenberg, Connie van Eeghen

Start Up: Cats, dogs, and the work involved… when working on everything else!  Kairn’s manuscript with Ben has been accepted – congratulations!  A recent court decision by the U.S. Ninth Circuit Court of Appeals defined “auditory processing disorder” as an “other health impairment” under the Individuals with Disabilities Education Act. It would be nice to have evidence base for diagnosis and accommodations.

1.                  Discussion: Karin’s lit review update
a.       Kairn has found the “Ear and Hearing” does publish systematic literature reviews
b.      The purpose of this discussion is to identify the kind of meaningful findings this review will include
c.       Kairn plans to evaluate different diagnostic dichotic listening tests to “support audiologists’ decisions about test selection and interpretation.”
                                                  i.      There are 9 recorded tests (some of which have several versions)
                                                ii.      There is no coherent biologic model to support these tests
                                              iii.      Many tests that have been used to support common models aren’t commercially available
                                              iv.      The commercially available tests are not well validated for reliability (and other domains – see below) or by rigorous trials
d.      The focus is comparing the tests and identifying whether any are supported for use
                                                  i.      There is plenty of literature reviewing the process of auditory testing, but none that review the tests themselves
                                                ii.      The concept of reliability also has to be well explained, as do the other domains:
1.      Reliability
2.      Accuracy
3.      Usefulness
4.      Value (not referenced in the literature – which should be so declared)
                                              iii.      Previous reviews reference correlation, which is not an adequate evaluation (this is for the Discussion section)
                                              iv.      Conclude with plan for next steps in research – of which the field is apparently wide open
e.       The methods section has been written; it originally used a broad net and this can be more tightly defined
f.       The objective of this review is to describe/summarize/identify/evaluate/summarize research studies that use any of these 9 tests and contain some evidence of reliability, accuracy, usefulness, and value.  Ben: Summarize the literature on reliability, accuracy, etc. for 9 commercially available tests.
                                                  i.      Eligibility criteria: Papers were eligible if they:
1.      One of 9 tests
2.      Children with normal hearing between ages 6 and 14 and are neurologically intact
3.      “We reported any test… with a gold standard diagnosis.”  (None meet this standard.)  Must reference reliability or accuracy or influenced care (useful) or good value for money.
4.      Or state as an exclusion: we will exclude any study that does not include reliability data or accuracy or usefulness or value
a.       Will not include review articles
                                                ii.      Intervention: reported results of these tests and any evidence
1.      Reliability: including correlation, Bland Altman plots, test-retest coefficients of variation, inter-rater reliability
2.      Accuracy: Kairn originally thought that since there is no agreement on “auditory processing,” there are no studies meeting this requirement.  Ben argued that the study is eligible for inclusion if it studies association with any reference test or gold standard.
a.       The fact that the accuracy data that does exist only includes brain tumor cases is still a reason to discuss it and to identify the opportunity to study accuracy in children who are neurologically intact
3.      Usefulness: TBD
4.      Value: TBD
                                              iii.      Quality issues:
1.      Sample size
g.      Next steps:
                                                  i.      Look at Kristi Johnson’s lit review on evaluating lymphedema diagnostic tools.
                                                ii.      Rewrite the methods section, focusing just on the steps related to selecting and analyzing the literature ONLY through the four elements of evaluation (nothing else).  One result of this will be a simple count of the number of articles that included each of the four elements.
1.      Stay close to the systematic review process
2.      OK to collect notes as a narrative assessment (or a grading system) on the quality of the studies (but this is NOT the purpose of the study – do NOT lose focus; this review will not lead to a high level quantitative study of the literature)
3.      Keep track of common evaluation criteria: age of study, size of sample, population of kids… 
                                              iii.      Define Usefulness and Value in an unambiguous way. 
                                              iv.      Sort the lit reviews based on the criteria for each of the four elements; document exactly where the evidence is that satisfies the criteria
h.      Remember: do not point out every deficiency in the study.  Stick to the focus: a story that convinces your colleagues that your evaluation is right – that no studies meet the criteria for evaluating auditory tests.
                                                  i.      One study (Wilson) looked for connections between any of the test results and parent surveys for children referred to clinic
                                                ii.      It did not include reliability data (like test/retest)
                                              iii.      It did perform linear regression, but not accuracy data
                                              iv.      The article may be reported separately as included in the original filter, but excluded due to lack of test-evaluative data

2.                  Next Workshop Meeting(s): Thursdays, 11:30 a.m. – 12:45 p.m., at Given Courtyard South Level 4.   Remember: the first 15 minutes are for checking in with each other.
a.       Sept 18: Marianne: draft of IRB application
b.      Sept 25: ???

Recorder: Connie van Eeghen

Thursday, September 11, 2014

Clinical Research Oriented Workshop (CROW) Meeting: Sept 4, 2014



Present:  Marianne Burke, Kat Cheung, Kairn Kelley, Amanda Kennedy, Rodger Kessler, Ben Littenberg, Connie van Eeghen

Start Up: Ben did a demonstration of a spontaneously dictated letter of support for Rodger and Connie’s SIM grant to the State of Vermont.   We also reviewed Rodger and Connie’s data flow management diagram and began to define the operational issues.  There is an obstacle regarding linkage of claims and clinical data.  Plan B is limited to incoming data streams from the practice EHRs that provide only primary care service information.  Incoming data streams from the all payers claims data might be able to match to primary care services from the EHRs.  This doesn’t provide patient level analysis, but may provide practice level analysis.

1.                  Discussion: Rodger and Connie: SIM grant draft review
a.       What data will be available for analysis:
                                                  i.      Facilitation data
                                                ii.      Clinical data
                                              iii.      Focus group
b.      It was not clear from the start that this is an intervention: MORE than just a demonstration/ observation project. 
                                                  i.      Which are being facilitated?  All 15? 
                                                ii.      Before and after comparisons
                                              iii.      What is the non-study comparator – for all the other practices we can know about?  In other words, how to evaluate secular trends?
1.      Before and after for arm 3
2.      Before and after for arms 1 and 2
c.       Suggestion: Identify 15 or more practices
                                                  i.      Recruit twice as many practices as can be facilitated (12 facilitated; 10-20 control; 30 total)
                                                ii.      Randomly assigned to intervention
1.      Two arms
a.       Integrated or not
b.      Improve VIP scores or not
                                                                                                                          i.      Do VIP scores correlate with outcomes
2.      Three arms, with sub-stratification to prevent downgrading
                                              iii.      Intervention for 18 months: use hard driving facilitation
                                              iv.      Compare integration with non-integration, using step-wedge (Rodger added this later)
d.      Questions
                                                  i.      Do VIP scores correlate with outcomes
                                                ii.      Can VT do integration: did VIP scores go up
                                              iii.      Did it make a difference: did changed VIP scores correlate with changed outcomes
                                              iv.      (Per Rodger, these questions are consistent with NCQA questions)
e.       Conclusion: 15 practices, all receiving facilitation over time, all with before/after comparisons of VIP and patient assessment scores

2.                  Next Workshop Meeting(s): Thursdays, 11:30 a.m. – 12:45 p.m., at Given Courtyard South Level 4.   Remember: the first 15 minutes are for checking in with each other.
a.       Sept 11: Kairn: draft of lit review
b.      Sept 18: Marianne: draft of IRB application
c.       Sept 25: ???

Recorder: Connie van Eeghen

Wednesday, September 10, 2014

Health Information National Trends Survey data available

The latest nationally representative dataset from the National Cancer Institute's Health Information National Trends Survey (HINTS) is now available for public download at http://hints.cancer.gov. This new dataset, as well as all previously released HINTS data, are currently available in SPSS, SAS, and STATA formats. 

Since 2003, HINTS has been monitoring changes in the evolving field of health communication and health information technology - providing comprehensive trend data on how Americans find, use, and understand health information. HINTS also assesses cancer information access and use, cancer risk perceptions, nutrition and physical activity behavior, and tobacco use. For the first time with this release, modules have been included on genetics and cancer and attitudes about medial research.

Not interested in analyzing the data? HINTS also provides a quick snapshot of each survey item in an easy-to-digest format that affords rapid insight into important changes in health communication and information sharing and effective communication channels and strategies with the aim to reduce the burden of cancer.

HINTS data has been used by survey researchers, public health practitioners, program planners, social scientists, and graduate students to gain insights into changing patterns, needs, and information opportunities in health communication. HINTS has also been designated as a data source for tracking several Healthy People 2020 objectives related to health communication and health information technology. HINTS also assesses progress related to other strategic public initiatives such as those related to patient-centered outcomes research, health care reform and accountability, and a greater interest in learning about or participating in clinical trials.

HINTS Widgets

Visit http://hints.cancer.gov/widgets.aspx to access all HINTS widgets.

What is a widget?
o    Widgets are online applications built by one web site that can be displayed on another web site.
o    A widget is an application that displays the featured content directly on your web page. You can embed content in personalized home pages, blogs, and other sites. Once you've added the widget, there's no technical maintenance. The hints.cancer.gov web site will update the content automatically.

How do you place a widget on your website?
Simply copy and paste the HTML code by selecting "Embed Code" in the "Share This" drop down into your web page.
For more information, visit http://hints.cancer.gov.

Mental Health, Substance Abuse, and Health Behavior Services in Patient-Centered Medical Homes


Congratulations to Rodger Kessler, Amanda Kennedy, Ben Littenber, Charlie MacLean Connie van Eeghen, and colleagues for their latest publication.​

Mental Health, Substance Abuse, and Health Behavior Services in Patient-Centered Medical Homes
Rodger Kessler, Benjamin F. Miller, Mark Kelly, Debbie Graham, Amanda Kennedy, Benjamin Littenberg, Charles D. MacLean, Constance van Eeghen, Sarah Hudson Scholle, Manasi Tirodkar, Suzanne Morton, and Wilson D. Pace
J Am Board Fam Med September-October 2014; 27:637-644; doi:10.3122/jabfm.2014.05.140021

Abstract

Purpose: The purpose of this study was to understand mental health, substance use, and health behavior activities within primary care practices recognized by the National Committee for Quality Assurance as patient-centered medical homes (PCMHs).
Methods: We identified 447 practices with all levels of National Committee for Quality Assurance PCMH recognition as of March 1, 2010. We selected the largest practice from multisite groups, and 238 practices were contacted. We received 123 responses, for a 52% response rate. A 40-item web-based survey was collected.
Results: Of PCMH practices, 42% have a behavioral health clinician on site; social workers were the most frequent category of provider delivering behavioral services. There are also were care managers—distinct from behavioral health clinician—at 62% of practices. Surveyed practices were less likely to have procedures for referrals, communication, and patient scheduling for responding to mental health and substance use services than for other medical subspecialties (50% compared with 73% for cardiology and 69% for endocrinology). More than half of practices (62%) reported using electronic, standardized depression screening and monitoring; practices were less likely to screen for substance use than mental health. Among the practices, 54% used evidence-based health behavior protocols for mental health and substance use conditions. Practices reported that lack of reimbursement, time, and sufficient knowledge were obstacles. Practices serving a higher proportion of low-income patients performed more mental health organizational and clinical activities.
Conclusions: In PCMHs, practice organization and response to behavioral issues seem to be less well developed than other types of medical care. These results support further efforts to develop whole-person care in the PCMH, with greater emphasis on access to and coordination of mental health, substance abuse, and health behavior services. Focusing primary care practices on this aspect of whole-person care will benefit from program sponsors' support and rewarding better integration with behavioral health.

Tuesday, September 9, 2014

Kessler publishes again!

Rodger Kessler, PhD, Assistant Professor of Family Medicine, has just had another article published. He's on a roll!

  • C. J. Peek, 
  • Russell E. Glasgow, 
  • Kurt C. Stange, 
  • Lisa M. Klesges,
  • E. Peyton Purcell, 
  • and Rodger S. Kessler
The 5 R’s: An Emerging Bold Standard for Conducting Relevant Research in a Changing WorldAnn Fam Med September/October 2014 12:447-455;doi:10.1370/afm.1688http://annfammed.org/content/12/5/447.abstract

Wednesday, September 3, 2014

Clinical Research Oriented Workshop (CROW) Meeting: Aug 28, 2014



Start Up: Recent VPR story about salmonella outbreaks on chicken farms document a QI project that focused on one farm’s processing method for dismembering previously clean chickens that led to the hen house as the vector.

1.                  Discussion: Kairn: draft of literature review/ quality improvement (QI) project
a.       Goal: approach the literature review for the dissertation as a QI project.  FOCUS: Efficient progress on dissertation as a whole and lit review with attention to specific process steps.
b.      Baseline measure: minutes/article.  Original goal: process and document 2 articles daily for literature review.
c.       Learnings: mapping out the process steps was helpful. It resulted in a new goal: process as many articles as possible to complete the dissertation, with minimum time in processing (selection, technical activities).  Moving to Zotera was helpful, which finds the citation from the pdf. Minutes/article dropped from 60 to 46 (a 23% reduction but still long for the goal of completion).
d.      Next steps: move key columns from Excel to Zotero and further reduce process steps.  Select articles based on holes that need to be filled.  Kairn estimates that she has about twenty articles left to read and will be complete in two weeks.

2.                  Next Workshop Meeting(s): Thursdays, 11:30 a.m. – 12:45 p.m., at Given Courtyard South Level 4.   Remember: the first 15 minutes are for checking in with each other.
a.       Sept 4: Rodger: SIM grant draft review
b.      Sept 11: Kairn: draft of lit review
c.       Sept 18: Marianne: draft of IRB application
d.      Sept 25: Ben (with Derek Lubetkin): draft of a paper on "Availability of US State Driver’s License Data for Obesity Research" - under the cone of silence.

Recorder: Connie van Eeghen