Pathology Grand Rounds 10/15/2014
Michael Criqui, MD, MPH
New Markers for Cardiovascular Disease Risk Prediction –
Coronary Artery Calcium Density and Abdominal Aortic Calcium
Dr. Criqui discussed his recent publication in ATVB
(Arterioscler Thromb Vasc Biol. 2014;34:1574-1579) where abdominal aortic
calcium (AAC) and coronary artery calcium (CAC) were evaluated for their
predictive value for incident coronary events.
AAC and CAC data were from computed tomographic scans of 1974 men and
women randomly selected form the Multi-Ethnic Study of Atherosclerosis. In this cohort both CAC and AAC were found to
be independently predictive of both cardiovascular disease and coronary heart
disease; while only AAC was found to be independently predictive of cardiovascular
disease mortality. Further study is
needed to determine the clinical value of screening for AAC and its use in risk
assessment.
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