Tuesday, May 31, 2011

Clinical Research Oriented Workshop (CROW) Meeting: May 27, 2011

Present: Liz Chen, Kairn Kelley, Rodger Kessler, Ben Littenberg

1. Kairn: Dichotic Words Test (DWT) Updates

a. Side project: working with the complex systems engineers to group the words based on their acoustic characteristics into self-organizing maps (SOMs)

b. Dissertation project: looking at how the use of the DWT for assessing children with ADHD

i. Study question: Do children with ADHD exhibit better test-retest reliability for short-lists from the DWT than long lists?

ii. Issue: a former collaborator and designer of the Dichotic Words Test may need to be contacted as the research might not support the use of the test

1. No legal barriers exist as to the way Kairn plans to use the test (it was provided without restrictions)

2. Concerns about affect on relationships or standing in the audiology community can be addressed by appropriate communication up front

iii. Outcome: Kairn will send her former collaborator an email expressing her intent to use the test for her dissertation.

2. Next Workshop Meeting(s): Thursday, 2:30 p.m. – 4:00 p.m., at Given Courtyard Level 4

a. June 2: Abby (no Connie)

b. June 9: Connie (no Amanda?)

c. June 16:

d. June 23: (no Ben at 3:30, no Amanda)

e. June 30:

f. Change to new time for our meetings for July and August: Thursday morning 9:30 – 11:00

g. Ben is on vacation July 16 – 30 and out Aug 4; Abby is on vacation August; Amanda is teaching Tues & Thurs 1 – 4 from July 1 – Aug 26

h. Future agenda to consider:

i. Rodger: Mixed methods article; article on Behavior’s Influence on Medical Conditions (unpublished)

ii. Future: Review of different types of journal articles (lit review, case study, original article, letter to editor…), when each is appropriate, tips on planning/writing (Abby)

Recorder: Kairn Kelley

Saturday, May 28, 2011

Amanda Kennedy Named Pharmacist of the Year

The Vermont Society of Health System Pharmacists has named Assistant Professor of Medicine Amanda Kennedy, PharmD BCPS ,as the 2011 Pharmacist of the Year. This annual award to a pharmacist is based on peer nominations and was presented to Dr. Kennedy at the society's annual meeting on May 25.  In addition to receiving the award, Dr. Kennedy also presented "Primary Care Prescribing in Vermont: A Research Update."

Many congratulations, Amanda!

--
Benjamin Littenberg, MD
Henry and Carleen Tufo Professor of Medicine and Professor of Nursing
University of Vermont
89 Beaumont Avenue, Room S459, Burlington, Vermont 05405
802-656-4560 fax 802-656-4576


Wednesday, May 25, 2011

GE Healthcare and Thomson Reuters Create Powerful, Precise Clinical Research Dataset

Sent by my husband, who works for GE Healthcare in Burlington.
Kairn


HOT OFF THE PRESS

— AMERICAS NEWSFLASH —
Jim Corrigan, Senior Vice President and General Manager, Americas Region




GE Healthcare and Thomson Reuters Provide Analytics on Powerful, Precise Clinical Research Dataset
Research Data Repository Combines Millions of De-identified Healthcare Claims and Electronic Medical Records to Measure the Efficacy of Drugs and Other Treatments

BARRINGTON, Ill. and NEW YORK – May 25, 2011 —Pharmaceutical firms and other healthcare organizations will now be able to conduct evidence-based research on data that enables them to better quantify the effectiveness of medical treatments on discrete patient populations , thanks to a new data and analytics solution developed and delivered by GE Healthcare and Thomson Reuters.

When needed to answer appropriate population-based health economics and outcomes research questions, healthcare analytics teams at General Electric (NYSE: GE) and Thomson Reuters (NYSE: TRI) now have the ability to combine commonly used outcomes research data from the Thomson Reuters MarketScan® Research Databases with de-identified electronic medical records data, while maintaining patient privacy and full compliance with HIPAA standards.. As a result, researchers and physicians can now gain new evidence-based insights into treatment protocols. These insights can help drive improved health outcomes.

The addition of de-identified clinical data provided by healthcare providers using EMR means a research study can evaluate medical treatments — commonly called “outcomes research” or “comparative effectiveness research.” The addition of the de-identified clinical data from the EMR means a research study can link de-identified claims data from a population of patients diagnosed with a particular condition such as hypertension, with de-identified clinical data on everything from a patient’s body mass index, blood pressure, symptoms and more. This research would provide more specific evidence to enable clinicians and patients to make better informed decisions.

“We’ve tackled what was once considered an insurmountable barrier to outcomes-based research,” said Dr. Brandon Savage, MD, Chief Medical Officer at GE Healthcare IT. “We’re extremely enthusiastic about the opportunities this discovery creates for the field and the improvements it may someday bring to patient care, across the world.”

Researchers from GE Healthcare and Thomson Reuters first demonstrated this approach to linking de-identified data in a presentation at the annual meeting of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) held in Atlanta in May 2010.

The ISPOR presentation, which used hypertension as a sample set, combined de-identified clinical data collected from more than 9,000 electronic medical records with MarketScan claims and prescription data from more than 30 million individuals. Each dataset has since grown considerably, resulting in an increasingly powerful data source.

Teams from both organizations have developed algorithms which enable the de-identification of patient data without loss of utility.

The companies subsequently proved the ability to use these proprietary methodologies to link additional therapeutic areas. They have now entered into a partnership to provide research and analytical services based on this proven capability.

“We can now conduct studies that assess the effectiveness of medical treatments, prescription adherence, and disease management initiatives based on both a deep set of clinical data and extensive data on the complete healthcare experience of a de-identified patient. This includes all hospitalizations and ambulatory visits as well as all filled prescriptions, costs, and reimbursements,” said Bill Marder, senior vice president at Thomson Reuters.

The companies are now engaging customers and planning studies that will demonstrate the value of these unique and comprehensive capabilities. For more information, please e-mail cds@ge.com or marketscan@thomsonreuters.com.

ABOUT GE HEALTHCARE:
GE Healthcare provides transformational medical technologies and services that are shaping a new age of patient care. Our broad expertise in medical imaging and information technologies, medical diagnostics, patient monitoring systems, drug discovery, biopharmaceutical manufacturing technologies, performance improvement and performance solutions services help our customers to deliver better care to more people around the world at a lower cost. In addition, we partner with healthcare leaders, striving to leverage the global policy change necessary to implement a successful shift to sustainable healthcare systems.

Our "healthymagination" vision for the future invites the world to join us on our journey as we continuously develop innovations focused on reducing costs, increasing access and improving quality and efficiency around the world. Headquartered in the United Kingdom, GE Healthcare is a $17 billion unit of General Electric Company (NYSE: GE). Worldwide, GE Healthcare employs more than 46,000 people committed to serving healthcare professionals and their patients in more than 100 countries. For more information about GE Healthcare, visit our website at www.gehealthcare.com.

ABOUT THOMSON REUTERS:
Thomson Reuters is the world's leading source of intelligent information for businesses and professionals. We combine industry expertise with innovative technology to deliver critical information to leading decision makers in the financial, legal, tax and accounting, healthcare and science and media markets, powered by the world's most trusted news organization. With headquarters in New York and major operations in London and Eagan, Minnesota, Thomson Reuters employs 55,000 people and operates in over 100 countries. For more information, go to www.thomsonreuters.com.


©2011 General Electric Company. All rights reserved.

Tuesday, May 17, 2011

About those Power Points

Another opinion on PowerPoint slides as a communication device; this with a political jibe:

Romney, you can’t govern by bullet point

And, if my attempt at creating a link didn't work, copy and paste this in your browser:

http://www.washingtonpost.com/opinions/romney-you-cant-govern-by-powerpoint/2011/05/17/AFVOS45G_story.html?wpisrc=emailtoafriend

Sunday, May 15, 2011

Clinical Research Oriented Workshop (CROW) Meeting: May 12, 2011

Clinical Research Oriented Workshop (CROW) Meeting: May 12, 2011

Present: Abby Crocker, Kairn Kelley, Amanda Kennedy, Rodger Kessler, Ben Littenberg, Connie van Eeghen

1. Check In: Beautiful day! Abby has been teaching and working on curriculum development – hard work, but important. Additional interesting discussion on the structure and use of teaching staff responsibilities and work load as a lecturer. Welcome Kairn – and everyone else.

2. Abby: Does hemoglobin A1C affect height in children with Type 1 diabetes? Planned presentation:

a. Background: high frequency of diagnosis; relationship to insulin deficiency

b. Research question

c. Literature review

d. Epidemiology of Type 1 DM in children

i. Insulin deficiency is related to undesirable complications and height retardation

e. Methods: data source, patient inclusion, study group size, clinical follow up plan

f. Data collection/management issues and basis for choosing a particular statistical model

i. When context is important (such as age, when measuring children’s height), then the model has to manage changes in the context as well as changes in the variable of interest

g. Statistical analysis: generalized linear mixed model

h. Results: graphically represent all possible data points (that is, axes intersect at 0,0)

i. Standard review of patients

ii. Univariate results

iii. GLMM results

i. Discussion

i. What do the results mean? Cost relationships?

ii. Implications regarding biology or clinical care or public policy

iii. Limitations (and Next Steps if appropriate)

j. Conclusions on the relationship between glycemic control and height

k. “Thank you” to collaborators - ? It depends on the relationships you want to foster.

3. PowerPoint Pointers

a. Animation: minimal, when functionally supported

b. Handouts: distribute after presentation

c. “B” and “W” to black or white out screen

d. F5 to start slide show

e. Package the PPT for the specific presentation

f. Shorter is better

4. Next Workshop Meeting(s): Thursday, 2:30 p.m. – 4:00 p.m., at Given Courtyard Level 4

a. May 19: Rodger: outline of 10 minute NCQA platform presentation for Academy Health (no Connie, Amanda, Abby, Kairn)

b. May 26: Kairn (no Connie)

c. June 2: Abby (no Connie)

d. June 9: Connie (no Amanda?)

e. June 16:

f. June 23: (no Ben at 3:30, no Amanda)

g. June 30:

h. Revisit the day/time for our meeting for July and August: Thursday morning 9:30 – 11:00

i. Ben is on vacation July 16 – 30 and out Aug 4; Abby is on vacation August; Amanda is teaching Tues & Thurs 1 – 4 from July 1 – Aug 26

j. Future agenda to consider:

i. Rodger: Mixed methods article; article on Behavior’s Influence on Medical Conditions (unpublished)

ii. Future: Review of different types of journal articles (lit review, case study, original article, letter to editor…), when each is appropriate, tips on planning/writing (Abby)

Recorder: Connie van Eeghen