UVM Clinical and Translational Science (CTS): P hacking

Wednesday, October 20, 2021

P hacking

Here is a brief (5:05) video on a big problem we should all know about.

FYI

https://youtu.be/i60wwZDA1CI

Benjamin Littenberg, MD
Henry and Carleen Tufo Professor of Medicine and Professor of Nursing
University of Vermont

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What the authorities say...about authority

It is wrong always, everywhere, and for anyone, to believe anything upon insufficient evidence. -William Kingdon Clifford (1845-1879)

There is no great invention, from fire to flying, which has not been hailed as an insult to some god. -J.B.S. Haldane, (1892-1964)

What has occurred over the course of the last few centuries is a growing (but by no means universal or certain) recognition that science gets the job done, while religion makes excuses. Sometimes they are very pretty excuses that capture the imagination of the public, but ultimately, when you want to win a war or heal a dying child or get rich from a discovery or explore Antarctica, you turn to science and reason, or you fail. -PZ Myers, (b. 9 Mar 1957)

Most institutions demand unqualified faith; but the institution of science makes skepticism a virtue. - Robert King Merton (1910-2003)

One should as a rule, respect public opinion in so far as is necessary to avoid starvation and to keep out of prison, but anything that goes beyond this is voluntary submission to an unnecessary tyranny, and is likely to interfere with happiness in all kinds of ways...- Bertrand Russell (1872-1970)

In all life one should comfort the afflicted, but verily, also, one should afflict the comfortable, and especially when they are comfortably, contentedly, even happily wrong. - John Kenneth Galbraith (1908-2006)

Historically, the claim of consensus has been the first refuge of scoundrels; it is a way to avoid debate by claiming that the matter is already settled.- Michael Crichton (1942-2008)

Unthinking respect for authority is the greatest enemy of truth. -Albert Einstein (1879-1955)

In questions of science, the authority of a thousand is not worth the humble reasoning of a single individual. -Galileo Galilei (1564-1642)

Every great advance in natural knowledge has involved the absolute rejection of authority. -Thomas Henry Huxley (1825-1895)

Handy Resources for doing CTS

Research Methods Knowledge Base

A comprehensive web-based textbook that addresses all of the topics in a typical introductory undergraduate or graduate course in social research methods.

NIH Resource for Behavioral and Social Science Research

A textbook of Behavioral and Social Science theory and methods for use in health research.

Duke Research Methods Wiki

Templates, examples, and tutorials for designing, conducting, and reporting clinical research.

Equator Network

Advice and guidelines on Reporting Health Research. CONSORT Checklist, etc.

SGIM Database of Secondary Research Databases

A catalog of (mostly national) databases that are available for secondary analyses

AHRQ Funding Opportunities
Grants for research and training.

NIH Application Help

Tips and advice on how to handle the process and paperwork for grant applications.

PhenX Toolkit

Standardized instruments to measure epidemiological and phenotypical characteristics of subjects.

Stata Cheat Sheets

Because Stata...

Journal/Author Name Estimator

Where to submit? Jane suggests journals for your masterpiece.

Writing: Verb Tenses

Useful and readable section-by-section advice on when to use past, present, future, and even the dreaded "perfect" tenses in your manuscripts.

The Directory of Open Access Journals

DOAJ is a community-curated online directory that indexes and provides access to high quality, open access, peer-reviewed journals. Most are also free to publish.

UVM Clinical and Translational Science (CTS)

Wednesday, October 20, 2021

P hacking

No comments:

Post a Comment

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